Management of Fatigue in Post-Stroke Patients


  • Ni Luh Putu Thrisna Dewi Professional Nurse Program, STIKES Wira Medika Bali, Indonesia
  • Anak Agung Sri Sanjiwani Bachelor of Nursing Program, STIKES Wira Medika Bali, Indonesia
  • Ni Made Nopita Wati Bachelor of Nursing Program, STIKES Wira Medika Bali, Indonesia
  • Ketut Lisnawati Bachelor of Nursing Program, STIKES Wira Medika Bali, Indonesia



fatigue management, stroke


Post-stroke patients often have sequelae that are difficult to avoid. One of the impacts that can occur after a stroke is the onset of cognitive impairment, physical disability, and even death due to the extent of brain damage that occurs. Another impact of stroke is Fatigue Post Stroke (FPS), where most stroke patients experience fatigue, and this condition can persist even though other symptoms caused by stroke have improved. This literature review aims to determine the appropriate management of fatigue after a stroke. The method in this study is a literature review by collecting published literature from databases such as ResearchGate, Google Scholar, and PLOS using Boolean stroke management and post-stroke fatigue. The literature search focused on articles related to fatigue in stroke patients. Both used RCT (Randomized Control Trial) design, Quasi Experiment, Qualitative study, and Survey study from the year (2015-2022).  Based on the results of data extraction from the author, two themes can be taken by the author, post-stroke patients who experience fatigue and fatigue management in stroke. The update in this literature review is the manifestation of fatigue conditions that, on average, will be experienced by stroke patients. If not handled properly, it will have a worse impact physically and psychologically, which can certainly interfere with the recovery process. So, it is necessary to appropriately manage both physical exercise and psychological interventions following the fatigue conditions of post-stroke patients. We recommend that in health services, nurses pay more attention to patient responses related to fatigue to provide appropriate nursing interventions and increase patients' desire to undergo rehabilitation.


Aali, G., Drummond, A., Das Nair, R., & Shokraneh, F. (2020). Post-stroke fatigue: a scoping review. F1000 Research, 1–24.

Choi-Kwon, S., Mitchell, P. H., & Kim, J. S. (2015). Nursing interventions for poststroke fatigue. Stroke, 46(10), e224–e227.

Cumming, T. B., Packer, M., Kramer, S. F., & English, C. (2016). The prevalence of fatigue after stroke: A systematic review and meta-analysis. International Journal of Stroke, 11(9), 968–977.

Dewi, N. L. P. T., Arifin, M. T., & Ismail, S. (2020). The influence of gayatri mantra and emotional freedom technique on quality of life of post-stroke patients. Journal of Multidisciplinary Healthcare, 13, 909–916.

Divyasita, C. I. W., Dewi, N. L. P. T., & Gunahariati, N. N. (2022). Gambaran Tingkat Fatigue Pasien Stroke yang Mengalami Serangan Berulang di RSU X Ubung. Jik Jurnal Ilmu Kesehatan, 6(2), 416.

Fibriansari, R. D., & Azizah, L. N. (2023). Yoga Therapy for Improving the Quality of Life among Breast Cancer Patients: Literature Review. Health and Technology Journal (HTechJ), 1(2), 139–147.

Ghaffari, A., Asadi, B., Zareian, A., Akbarfahimi, M., Raissi, G. R., & Fathali Lavasani, F. (2022). The Effects of Vestibular Rehabilitation on Poststroke Fatigue: A Randomized Controlled Trial Study. Stroke Research and Treatment, 2022, 1–9.

Jin, C., Cho, S. Y., Park, S. U., Jung, W. S., Moon, S. K., Park, J. M., ... & Kwon, S. (2019). Buyang Huanwu Tang (Boyang Hwano Tang) for the treatment of post-stroke fatigue: protocol for a systematic review of randomized controlled trials. Medicine, 98(37).

Kjeverud, A., Østlie, K., Schanke, A. K., Gay, C., Thoresen, M., & Lerdal, A. (2020). Trajectories of fatigue among stroke patients from the acute phase to 18 months post-injury: A latent class analysis. PLoS ONE, 15(4), 1–14.

Kurniyawan, E. H., Andriyani, A., Wuriyaningsih, E. W., Dewi, E. I., Yunanto, R. A., Deviantony, F., & Fitria, Y. (2023). Self-efficacy and Job Stress among Tobacco Farmers. Health and Technology Journal (HTechJ), 1(3), 236–242.

Mead, G., Gillespie, D., Barber, M., House, A., Lewis, S., Ensor, H., Wu, S., & Chalder, T. (2022). Post stroke intervention trial in fatigue (POSITIF): Randomised multicentre feasibility trial. Clinical Rehabilitation, 36(12), 1578–1589.

Nguyen, S., Wong, D., McKay, A., Rajaratnam, S. M., Spitz, G., Williams, G., ... & Ponsford, J. L. (2019). Cognitive behavioural therapy for post-stroke fatigue and sleep disturbance: a pilot randomised controlled trial with blind assessment. Neuropsychological rehabilitation, 29(5), 723-738.

Noor, M. A. (2018). Gambaran Karakteristik Fatigue Pasien Post Stroke. Nurscope : Jurnal Keperawatan Dan Pemikiran Ilmiah, 4(7), 55–60.

Nugraha. (2018). Kelelahan pada Pasien dengan Penyakit Kronis. Prosiding Seminar Bakti Tunas Husada. E-Jurnal STIKes Bakti Tunas Husada Tasikmalaya, 49(April), 7–13.

Ponchel, A., Bombois, S., Bordet, R., & Hénon, H. (2015). Factors Associated with Poststroke Fatigue: A Systematic Review. Stroke Research and Treatment, 2015, 347920.

Pramana, P. Y., Sintarani, C. I. D. S., Wijayanti, I. A. S. W., & Sudewi, A. A. R. S. (2022). Hubungan fungsi motorik dan derajat kekuatan otot dengan kejadian fatigue pasca stroke. Intisari Sains Medis, 13(2), 560–564.

Pratiwi, W. A. Y., Wuryaningsih, E. W., & Kurniyawan, E. H. (2022). Pengaruh Relaksasi Otot Progresif terhadap Kelelahan dan Kualitas Tidur pada Petani Penyadap Karet di PTPN XII Kebun Kalisanen Jember. Pustaka Kesehatan, 10(2), 89-94.

Puspita, V. T., & Kariasa, I. M. (2020). Manajemen Fatigue Post Stroke Secara Non Fisik, Apakah Efektif. Dunia Keperawatan: Jurnal Keperawatan Dan Kesehatan, 8(2), 294.

Thomas, K. (2020). Understanding Post-Stroke Fatigue. Department of Public Health and Primary Care School of Clinical Medicine Lucy Cavendish College University of Cambridge, October.

Visser, M. M., Goodin, P., Parsons, M. W., Lillicrap, T., Spratt, N. J., Levi, C. R., & Bivard, A. (2019). Modafinil treatment modulates functional connectivity in stroke survivors with severe fatigue. Scientific reports, 9(1), 9660.

WHO. (2017). (World Health Organization). Top 10 causes of death worldwide. Retrieved from

Wu, S., Chalder, T., Anderson, K. E., Gillespie, D., Macleod, M. R., & Mead, G. E. (2017). Development of a psychological intervention for fatigue after stroke. PLoS ONE, 12(8).

Zhang, S., Cheng, S., Zhang, Z., Wang, C., Wang, A., & Zhu, W. (2021). Related risk factors associated with post-stroke fatigue: a systematic review and meta-analysis. Neurological Sciences, 42, 1463-1471.




How to Cite

Thrisna Dewi, N. L. P., Sanjiwani, A. A. S., Wati, N. M. N., & Lisnawati, K. (2023). Management of Fatigue in Post-Stroke Patients. Health and Technology Journal (HTechJ), 1(4), 356–363.